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1l8c

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Image:1l8c.png

Template:STRUCTURE 1l8c

STRUCTURAL BASIS FOR HIF-1ALPHA/CBP RECOGNITION IN THE CELLULAR HYPOXIC RESPONSE

Template:ABSTRACT PUBMED 11959977

About this Structure

1L8C is a 2 chains structure with sequences from Homo sapiens and Mus musculus. The February 2010 RCSB PDB Molecule of the Month feature on Enhanceosome by David Goodsell is 10.2210/rcsb_pdb/mom_2010_2. Full experimental information is available from OCA.

Reference

  • Dames SA, Martinez-Yamout M, De Guzman RN, Dyson HJ, Wright PE. Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5271-6. PMID:11959977 doi:http://dx.doi.org/10.1073/pnas.082121399

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