1sg1

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Template:STRUCTURE 1sg1

Contents

Crystal Structure of the Receptor-Ligand Complex between Nerve Growth Factor and the Common Neurotrophin Receptor p75

Template:ABSTRACT PUBMED 15131306

Disease

Known disease associated with this structure: Neuropathy, hereditary sensory and autonomic, type V OMIM:[162030]

About this Structure

1SG1 is a 3 chains structure with sequences from Homo sapiens and Rattus norvegicus. The August 2005 RCSB PDB Molecule of the Month feature on Neurotrophins by David S. Goodsell is 10.2210/rcsb_pdb/mom_2005_8. Full crystallographic information is available from OCA.

Reference

  • He XL, Garcia KC. Structure of nerve growth factor complexed with the shared neurotrophin receptor p75. Science. 2004 May 7;304(5672):870-5. PMID:15131306 doi:10.1126/science.1095190

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