3iu3

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Image:3iu3.jpg

Template:STRUCTURE 3iu3

Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain

Template:ABSTRACT PUBMED 20032294

About this Structure

3IU3 is a 9 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Du J, Yang H, Zhang D, Wang J, Guo H, Peng B, Guo Y, Ding J. Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab. J Immunol. 2010 Feb 1;184(3):1361-8. Epub 2009 Dec 23. PMID:20032294 doi:10.4049/jimmunol.0903178

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