2x0u
From Proteopedia
STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO A 2-AMINO SUBSTITUTED BENZOTHIAZOLE SCAFFOLD
About this Structure
2X0U is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838
Page seeded by OCA on Wed Jan 27 19:55:31 2010
Categories: Homo sapiens | Basse, N. | Fersht, A R. | Joerger, A C. | Kaar, J L. | Activator | Apoptosis | Cancer | Cell cycle | Host-virus interaction | Li-fraumeni drug discovery | Metal binding | Protein stabilization | Surface crevice | Transcription | Transcription factor | Transcription regulation | Tumor suppressor