2x0w
From Proteopedia
STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO 5,6-DIMETHOXY-2-METHYLBENZOTHIAZOLE
About this Structure
2X0W is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838
Page seeded by OCA on Wed Jan 27 19:55:50 2010
Categories: Homo sapiens | Basse, N. | Fersht, A R. | Joerger, A C. | Kaar, J L. | Activator | Apoptosis | Cancer | Cell cycle | Drug discovery | Host-virus interaction | Li-fraumeni syndrome | Protein stabilization | Surface crevice | Transcription | Transcription factor | Transcription regulation | Tumor suppressor