3ia6

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Image:3ia6.png

Template:STRUCTURE 3ia6

X-ray Crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a PPAR gamma/alpha dual agonist

Template:ABSTRACT PUBMED 19783444

About this Structure

3IA6 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Casimiro-Garcia A, Bigge CF, Davis JA, Padalino T, Pulaski J, Ohren JF, McConnell P, Kane CD, Royer LJ, Stevens KA, Auerbach B, Collard W, McGregor C, Song K. Synthesis and evaluation of novel alpha-heteroaryl-phenylpropanoic acid derivatives as PPARalpha/gamma dual agonists. Bioorg Med Chem. 2009 Oct 15;17(20):7113-25. Epub 2009 Sep 6. PMID:19783444 doi:10.1016/j.bmc.2009.09.001

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