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3isj
From Proteopedia
Crystal structure of pantothenate synthetase from Mycobacterium tuberculosis in complex with 5-methoxy-N-(methylsulfonyl)-1H-indole-2-carboxamide
About this Structure
3ISJ is a 2 chains structure with sequences from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Hung AW, Silvestre HL, Wen S, Ciulli A, Blundell TL, Abell C. Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase. Angew Chem Int Ed Engl. 2009;48(45):8452-6. PMID:19780086 doi:10.1002/anie.200903821
Page seeded by OCA on Thu Jan 28 14:48:08 2010
Categories: Mycobacterium tuberculosis | Pantoate--beta-alanine ligase | Abell, C. | Blundell, T L. | Ciulli, A. | Hung, A W. | Silvestre, H L. | Wen, S. | Atp-binding | Cytoplasm | Fragment-based drug design | Ligase | Magnesium | Metal-binding | Nucleotide-binding | Pantothenate biosynthesis | Pantothenate synthetase
