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3kcg

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Image:3kcg.jpg

Template:STRUCTURE 3kcg

Contents

Crystal structure of the antithrombin-factor IXa-pentasaccharide complex

Template:ABSTRACT PUBMED 20080729

Disease

Known disease associated with this structure: Hemophilia B OMIM:[300746]

About this Structure

3KCG is a 3 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Johnson DJ, Langdown J, Huntington JA. Molecular basis of factor IXa recognition by heparin-activated antithrombin revealed by a 1.7-A structure of the ternary complex. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):645-50. Epub 2009 Dec 22. PMID:20080729

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