2pk8

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2pk8, resolution 1.85Å

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Crystal structure of an uncharacterized protein PF0899 from Pyrococcus furiosus

Overview

The hypothetical protein PF0899 is a 95-residue peptide from the, hyperthermophilic archaeon Pyrococcus furiosus that represents a gene, family with six members. P. furiosus ORF PF0899 has been cloned, expressed, and crystallized and its structure has been determined by the Southeast, Collaboratory for Structural Genomics (http://www.secsg.org). The, structure was solved using the SCA2Structure pipeline from multiple data, sets and has been refined to 1.85 A against the highest resolution data, set collected (a presumed gold derivative), with a crystallographic R, factor of 21.0% and R(free) of 24.0%. The refined structure shows some, structural similarity to a wedge-shaped domain observed in the structure, of the major capsid protein from bacteriophage HK97, suggesting that, PF0899 may be a structural protein.

About this Structure

2PK8 is a Single protein structure of sequence from Pyrococcus furiosus dsm 3638 with AUC as ligand. This structure superseeds the now removed PDB entry 1SHE. Full crystallographic information is available from OCA.

Reference

Structure of the hypothetical protein PF0899 from Pyrococcus furiosus at 1.85 A resolution., Kelley LL, Dillard BD, Tempel W, Chen L, Shaw N, Lee D, Newton MG, Sugar FJ, Jenney FE Jr, Lee HS, Shah C, Poole FL 3rd, Adams MW, Richardson JS, Richardson DC, Liu ZJ, Wang BC, Rose J, Acta Crystallograph Sect F Struct Biol Cryst Commun. 2007 Jul 1;63(Pt, 7):549-52. Epub 2007 Jun 11. PMID:17620707

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