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Phosphoglucoisomerase

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Contents

Definition

Phosphoglucoisomerase (also known as phosphoglucose isomerase) are a group of enzymes of the isomerase family, that catalyze the transfer of a phosphate group from ATP to D-hexoses, such as D-glucose. The importance of these group of enzymes lies in the fact that

Structure

Mechanism

Crystal Structure of HUMAN PHOSPHOGLUCOSE ISOMERASE (PDB=1IAT[1])

Template:STRUCTURE 1iat

References

  1. ↑ Read J, Pearce J, Li X, Muirhead H, Chirgwin J, Davies C. The crystal structure of human phosphoglucose isomerase at 1.6 A resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia. J Mol Biol. 2001 Jun 1;309(2):447-63. PMID:11371164 doi:10.1006/jmbi.2001.4680
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