Phosphoglucoisomerase

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Contents

Definition

Template:STRUCTURE 1hox Phosphoglucoisomerase (also known as phosphoglucose isomerase) are a group of enzymes of the isomerase family, that catalyze the transfer of a phosphate group from ATP to D-hexoses, such as D-glucose. The importance of these group of enzymes lies in the fact that


Crystal Structure of RABBIT PHOSPHOGLUCOSE ISOMERASE COMPLEXED WITH FRUCTOSE-6-PHOSPHATE(PDB=1IAT[1]) Crystal Structure of HUMAN PHOSPHOGLUCOSE ISOMERASE (PDB=1IAT[2])

Structure

Mechanism

References

  1. ↑ Lee JH, Chang KZ, Patel V, Jeffery CJ. Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate. Biochemistry. 2001 Jul 3;40(26):7799-805. PMID:11425306
  2. ↑ Read J, Pearce J, Li X, Muirhead H, Chirgwin J, Davies C. The crystal structure of human phosphoglucose isomerase at 1.6 A resolution: implications for catalytic mechanism, cytokine activity and haemolytic anaemia. J Mol Biol. 2001 Jun 1;309(2):447-63. PMID:11371164 doi:10.1006/jmbi.2001.4680
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