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3l9h

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Image:3l9h.jpg

Template:STRUCTURE 3l9h

X-ray structure of mitotic kinesin-5 (KSP, KIF11, Eg5)in complex with the hexahydro-2H-pyrano[3,2-c]quinoline EMD 534085

Template:ABSTRACT PUBMED 20149654

About this Structure

3L9H is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Schiemann K, Finsinger D, Zenke F, Amendt C, Knochel T, Bruge D, Buchstaller HP, Emde U, Stahle W, Anzali S. The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1491-5. Epub 2010 Jan 25. PMID:20149654 doi:10.1016/j.bmcl.2010.01.110

Page seeded by OCA on Wed Mar 3 16:19:51 2010

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