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3inf

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Revision as of 14:45, 3 March 2010 by OCA (Talk | contribs)
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Image:3inf.jpg

Template:STRUCTURE 3inf

Bace1 with the aminohydantoin Compound 37

Template:ABSTRACT PUBMED 19968289

About this Structure

3INF is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Malamas MS, Erdei J, Gunawan I, Turner J, Hu Y, Wagner E, Fan K, Chopra R, Olland A, Bard J, Jacobsen S, Magolda RL, Pangalos M, Robichaud AJ. Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors. J Med Chem. 2010 Feb 11;53(3):1146-58. PMID:19968289 doi:10.1021/jm901414e

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