3m1n

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Image:3m1n.jpg

Template:STRUCTURE 3m1n

Contents

Crystal structure of Human Sonic Hedgehog N-terminal domain

Template:ABSTRACT PUBMED 10753901

Disease

Known disease associated with this structure: Coloboma, ocular OMIM:[600725], Holoprosencephaly-3 OMIM:[600725], Microphthalmia, isolated, with coloboma 5 OMIM:[600725], Solitary median maxillary central incisor OMIM:[600725]

About this Structure

3M1N is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Pepinsky RB, Rayhorn P, Day ES, Dergay A, Williams KP, Galdes A, Taylor FR, Boriack-Sjodin PA, Garber EA. Mapping sonic hedgehog-receptor interactions by steric interference. J Biol Chem. 2000 Apr 14;275(15):10995-1001. PMID:10753901

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