3ade

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Image:3ade.jpg

Template:STRUCTURE 3ade

Crystal Structure of Keap1 in Complex with Sequestosome-1/p62

Template:ABSTRACT PUBMED 20173742

About this Structure

3ADE is a 2 chains structure with sequences from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M. The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol. 2010 Mar;12(3):213-23. Epub 2010 Feb 21. PMID:20173742 doi:10.1038/ncb2021

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