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Rhiannon Khela

Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. Andrea Gorrell.

spinqualitylabelsall models PDB ID 2gls Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
2gls, resolution 3.50Å ()
Ligands:
Activity:	Glutamate--ammonia ligase, with EC number 6.3.1.2
Structural annotation: Resources: CATH : 2Glsa02, 2Glsa01, 2Glsb02, 2Glsb01, 2Glsc01, 2Glsc02, 2Glsd02, 2Glsd01, 2Glse02, 2Glse01, 2Glsf02, 2Glsf01, 2Glsg01, 2Glsg02, 2Glsh02, 2Glsh01, 2Glsi02, 2Glsi01, 2Glsj01, 2Glsj02, 2Glsk01, 2Glsk02, 2Glsl02, 2Glsl01 InterPro : Ipr014746, Ipr008146, Ipr001637, Ipr008147, Ipr004809 Pfam : PF00120, PF03951 SCOP : d2glsa2, d2glsa1, d2glsb2, d2glsb1, d2glsc1, d2glsc2, d2glsd2, d2glsd1, d2glse2, d2glse1, d2glsf1, d2glsf2, d2glsg2, d2glsg1, d2glsh2, d2glsh1, d2glsi2, d2glsi1, d2glsj2, d2glsj1, d2glsk1, d2glsk2, d2glsl2, d2glsl1 UniProt : P0A1P6
Functional annotation: Cellular component: cytoplasm Biological process: nitrogen compound metabolic process glutamine biosynthetic process nitrogen fixation Molecular function: ligase activity nucleotide binding glutamate-ammonia ligase activity catalytic activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, PDBsum, RCSB
Coordinates:	save as pdb, mmCIF, xml

Structure

According to Yahmeshita et. al., the unrefined structure is made of two layrs containing 6 subunits each, for a total of 12 subunits. ^[1] text text ^[2]

References

1. ↑ Yamashita MM, Almassy RJ, Janson CA, Cascio D, Eisenberg D. Refined atomic model of glutamine synthetase at 3.5 A resolution. J Biol Chem. 1989 Oct 25;264(30):17681-90. PMID:2572586
2. ↑ Kumada Y, Benson DR, Hillemann D, Hosted TJ, Rochefort DA, Thompson CJ, Wohlleben W, Tateno Y. Evolution of the glutamine synthetase gene, one of the oldest existing and functioning genes. Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):3009-13. PMID:8096645

Image:2gls120.png