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Sandbox 173
From Proteopedia
Rhodopsin is a highly characterized G protein-coupled receptor found in the neurons of the retina and in rod photoreceptor cells. It is part of the Class A (Family 1) of G protein-coupled receptors, a superfamily of membrane receptors with seven transmembrane helices[1]. G protein-coupled receptors mediate responses to visual, olfactory, hormonal, and neutransmitter signals among others[2].
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| 1u19, resolution 2.20Å () | |||||||||
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| Ligands: | , , , , , , , , | ||||||||
| Non-Standard Residues: | |||||||||
| Related: | 1f88, 1hzx, 1l9h | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Introduction
Structure
Characteristic G Protein-Coupled Receptor Architecture
About this structure[3].
Function
Light-Induced Visual Signal Transduction
Light absorption and G protein activation
Opsin
References
- Okada T, Sugihara M, Bondar AN, Elstner M, Entel P, Buss V. The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure. J Mol Biol. 2004 Sep 10;342(2):571-83. PMID:15327956 doi:10.1016/j.jmb.2004.07.044
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