Glycerol-3-Phosphate Dehydrogenase

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Glycerol 3-Phosphate Dehydrogenase

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Contents 1 Introduction 1.1 Structure 1.2 Function 1.2.1 Metabolism 1.3 Diseases

Introduction

Glycerol 3-Phosphate Dehydrogenase (GlpD) is an oxidoreductase enzyme. Oxidoreductase enzymes catalyze the reaction of transfer of electrons between molecules. GlpD is a membrane associated enzyme and is also the site where glycolysis, respiration and phospholipid biosynthesis in E. coli are linked together. In Ecoli, there are many newly discovered structures of GlpD that transfer electrons into the respiratory pathway. Also, metabolic pathways are involved in breaking down glycerol into precursors for other pathways. The GlpD enzyme contains a flavinactive site which plays a major role in the respiratory electron transport chain.

Structure

Function

Metabolism

Diseases

Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. Andrea Gorrell.