Glycerol-3-Phosphate Dehydrogenase

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Glycerol 3-Phosphate Dehydrogenase

Template:STRUCTURE 2r4e

Contents 1 Introduction 1.1 Structure 1.2 Function 1.2.1 Metabolism 1.3 Diseases

Introduction

Glycerol 3-Phosphate Dehydrogenase (GlpD) is an oxidoreductase enzyme which catalyze the reaction of transfer of electrons between molecules. GlpD is a membrane associated enzyme that is involved in glycerol metabolism, ubiquinone and glyceroneogenesis in E. coli. In Ecoli, many newly discovered structures of GlpD are being used to transfer electrons into the respiratory pathway and also for the metabolism of glycerol into its precursors for other pathways. The GlpD enzyme contains a flavin active site which plays a major role in the respiratory electron transport chain and in cellular energy requirements.

Structure

GlpD consists of two chains; α and β.

Function

Metabolism

Diseases

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