2j9i

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Image:2j9i.png

Template:STRUCTURE 2j9i

LENGSIN IS A SURVIVOR OF AN ANCIENT FAMILY OF CLASS I GLUTAMINE SYNTHETASES IN EUKARYOTES THAT HAS UNDERGONE EVOLUTIONARY RE-ENGINEERING FOR A TISSUE-SPECIFIC ROLE IN THE VERTEBRATE EYE LENS.

Template:ABSTRACT PUBMED 17161372

About this Structure

2J9I is a 12 chains structure with sequences from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Wyatt K, White HE, Wang L, Bateman OA, Slingsby C, Orlova EV, Wistow G. Lengsin is a survivor of an ancient family of class I glutamine synthetases re-engineered by evolution for a role in the vertebrate lens. Structure. 2006 Dec;14(12):1823-34. PMID:17161372 doi:http://dx.doi.org/10.1016/j.str.2006.10.008

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