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User:Reuben Chacko

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One of the CBI Molecules being studied in the University of Massachusetts Amherst Chemistry-Biology Interface Program at UMass Amherst and on display at the Molecular Playground.

""Glutathione""


Glutathione reductase

This protein maintains a reducing environment inside cells by reducing glutathione disulfide to glutathione. Glutathione reductase or GSR catalyzes this reaction by attacking glutahione disulfide nucleophilically via the Cys63 residue. The Cys63 nucleophile itself is generated by the nucleophilic attack of


Glutathione reductase showing glutathione disulfide (molecule with two yellow spheres) and FAD with its flat flavin moiety sitting up-close ready to carry out the nucleophilic attack.

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Reuben Chacko, Eran Hodis

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