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3l0v

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Revision as of 08:11, 5 May 2010 by OCA (Talk | contribs)
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Image:3l0v.png

Template:STRUCTURE 3l0v

Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket

Template:ABSTRACT PUBMED 20172725

About this Structure

3L0V is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yu W, Guo Z, Orth P, Madison V, Chen L, Dai C, Feltz RJ, Girijavallabhan VM, Kim SH, Kozlowski JA, Lavey BJ, Li D, Lundell D, Niu X, Piwinski JJ, Popovici-Muller J, Rizvi R, Rosner KE, Shankar BB, Shih NY, Siddiqui MA, Sun J, Tong L, Umland S, Wong MK, Yang DY, Zhou G. Discovery and SAR of hydantoin TACE inhibitors. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1877-80. Epub 2010 Feb 4. PMID:20172725 doi:10.1016/j.bmcl.2010.01.148

Page seeded by OCA on Wed May 5 11:11:44 2010

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