2kqp

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Template:STRUCTURE 2kqp

Contents

NMR Structure of Proinsulin

Template:ABSTRACT PUBMED 20106974

Disease

Known disease associated with this structure: Hyperproinsulinemia, familial, with or without diabetes OMIM:[176730]

About this Structure

2KQP is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Yang Y, Hua QX, Liu J, Shimizu EH, Choquette MH, Mackin RB, Weiss MA. Solution structure of proinsulin: connecting domain flexibility and prohormone processing. J Biol Chem. 2010 Mar 12;285(11):7847-51. Epub 2010 Jan 27. PMID:20106974 doi:10.1074/jbc.C109.084921

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