2kes

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Image:2kes.png

Template:STRUCTURE 2kes

Contents

Solution Structure of the Coiled-coil Domain of Synphilin-1

Template:ABSTRACT PUBMED 19762560

Disease

Known disease associated with this structure: Parkinson disease OMIM:[603779]

About this Structure

2KES is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Xie YY, Zhou CJ, Zhou ZR, Hong J, Che MX, Fu QS, Song AX, Lin DH, Hu HY. Interaction with synphilin-1 promotes inclusion formation of alpha-synuclein: mechanistic insights and pathological implication. FASEB J. 2010 Jan;24(1):196-205. Epub 2009 Sep 17. PMID:19762560 doi:10.1096/fj.09-133082

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