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3lb7
From Proteopedia
Crystal structure of C-RAF (Raf-1)
Template:ABSTRACT PUBMED 20130576
About this Structure
3LB7 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Hatzivassiliou G, Song K, Yen I, Brandhuber BJ, Anderson DJ, Alvarado R, Ludlam MJ, Stokoe D, Gloor SL, Vigers G, Morales T, Aliagas I, Liu B, Sideris S, Hoeflich KP, Jaiswal BS, Seshagiri S, Koeppen H, Belvin M, Friedman LS, Malek S. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth. Nature. 2010 Mar 18;464(7287):431-5. Epub 2010 Feb 3. PMID:20130576 doi:10.1038/nature08833
Page seeded by OCA on Wed May 12 10:34:45 2010
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Brandhuber, B J. | Morales, T. | Vigers, G. | Alternative splicing | Atp-binding | Disease mutation | Kinase | Kinase domain | Metal-binding | Nucleotide-binding | Phosphoprotein | Polymorphism | Proto-oncogene | Serine/threonine-protein kinase | Transferase | Zinc | Zinc-finger
