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3lb7

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Revision as of 07:34, 12 May 2010 by OCA (Talk | contribs)
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Image:3lb7.png

Template:STRUCTURE 3lb7

Crystal structure of C-RAF (Raf-1)

Template:ABSTRACT PUBMED 20130576

About this Structure

3LB7 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hatzivassiliou G, Song K, Yen I, Brandhuber BJ, Anderson DJ, Alvarado R, Ludlam MJ, Stokoe D, Gloor SL, Vigers G, Morales T, Aliagas I, Liu B, Sideris S, Hoeflich KP, Jaiswal BS, Seshagiri S, Koeppen H, Belvin M, Friedman LS, Malek S. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth. Nature. 2010 Mar 18;464(7287):431-5. Epub 2010 Feb 3. PMID:20130576 doi:10.1038/nature08833

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