3f7b

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Image:3f7b.png

Template:STRUCTURE 3f7b

Contents

Crystal Structure of soluble domain of CA4 in complex with small molecule.

Template:ABSTRACT PUBMED 20363633

Disease

Known disease associated with this structure: Retinitis pigmentosa-17 OMIM:[114760]

About this Structure

3F7B is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Vernier W, Chong W, Rewolinski D, Greasley S, Pauly T, Shaw M, Dinh D, Ferre RA, Nukui S, Ornelas M, Reyner E. Thioether benzenesulfonamide inhibitors of carbonic anhydrases II and IV: structure-based drug design, synthesis, and biological evaluation. Bioorg Med Chem. 2010 May 1;18(9):3307-19. Epub 2010 Mar 11. PMID:20363633 doi:10.1016/j.bmc.2010.03.014

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