3kgu

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Image:3kgu.png

Template:STRUCTURE 3kgu

Wild type human transthyretin (TTR) complexed with genistein (TTRwt:GEN) pH 7.5

Template:ABSTRACT PUBMED 20211733

About this Structure

3KGU is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Trivella DB, Bleicher L, Palmieri Lde C, Wiggers HJ, Montanari CA, Kelly JW, Lima LM, Foguel D, Polikarpov I. Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding. J Struct Biol. 2010 Jun;170(3):522-31. Epub 2010 Mar 6. PMID:20211733 doi:10.1016/j.jsb.2010.03.002

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