3knb

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Template:STRUCTURE 3knb

Contents 1 Crystal structure of the titin C-terminus in complex with obscurin-like 1 2 Disease 3 About this Structure 4 Reference

Crystal structure of the titin C-terminus in complex with obscurin-like 1

Template:ABSTRACT PUBMED 20489725

Disease

Known disease associated with this structure: Cardiomyopathy, dilated, 1G OMIM:[188840], Cardiomyopathy, familial hypertrophic OMIM:[188840], Muscular dystrophy, limb-girdle, type 2J OMIM:[188840], Myopathy, early-onset, with fatal cardiomyopathy OMIM:[188840], Myopathy, proximal, with early respiratory muscle involvement OMIM:[188840], Tibial muscular dystrophy, tardive OMIM:[188840]

About this Structure

3KNB is a 2 chains structure with sequences from Homo sapiens. This structure supersedes the now removed PDB entry 3irg. Full crystallographic information is available from OCA.

Reference

• Sauer F, Vahokoski J, Song YH, Wilmanns M. Molecular basis of the head-to-tail assembly of giant muscle proteins obscurin-like 1 and titin. EMBO Rep. 2010 Jul;11(7):534-40. Epub 2010 May 21. PMID:20489725 doi:10.1038/embor.2010.65

Page seeded by OCA on Wed Jun 2 08:10:56 2010