2kq6

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Image:2kq6.png

Template:STRUCTURE 2kq6

Contents

The structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity

Template:ABSTRACT PUBMED 20439752

Disease

Known disease associated with this structure: Polycystic kidney disease, adult, type II OMIM:[173910]

About this Structure

2KQ6 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Petri ET, Celic A, Kennedy SD, Ehrlich BE, Boggon TJ, Hodsdon ME. Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9176-81. Epub 2010 May 3. PMID:20439752

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