3mo2

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Image:3mo2.jpg

Template:STRUCTURE 3mo2

human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E67

Template:ABSTRACT PUBMED 20434463

About this Structure

3MO2 is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chang Y, Ganesh T, Horton JR, Spannhoff A, Liu J, Sun A, Zhang X, Bedford MT, Shinkai Y, Snyder JP, Cheng X. Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J Mol Biol. 2010 Jul 2;400(1):1-7. Epub 2010 Apr 29. PMID:20434463 doi:10.1016/j.jmb.2010.04.048

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