Sandbox DW1 002

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The Chemistry of Drugs in Forensic Science


What does the term DRUG mean

Drugs vs. Medicines

Drugs - Natural or synthetic compounds potentially used for physiological and psychological effects. 

       Medicinal Uses - to correct or help some physiological or psychological problem
       Drug Abuse - chemicals used/taken for purposes for which they were never intended.

Metabolic Poisons affect Biochemical Mechanisms. Examples of this class of poisons

Carbon Monoxide (Gas) - colorless, odorless, toxic - suicide or homocide. Binds to iron in hemoglobin and only very slowly is released - displacing oxygen - Carboxyhemoglobin is 140 time more stable than oxyhemoglobin Breathing 0.1% CO in air for 4 hours converts 60% of hemoglobin to carboxyhemoglobin! CO produced by incomplete combustion - 200 million tons in US annually Not a cumulative poison (given time, the free hemoglobin is released)

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