3m8q

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Image:3m8q.png

Template:STRUCTURE 3m8q

HIV-1 RT with AMINOPYRIMIDINE NNRTI

Template:ABSTRACT PUBMED 20538456

About this Structure

3M8Q is a 2 chains structure with sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Kertesz DJ, Brotherton-Pleiss C, Yang M, Wang Z, Lin X, Qiu Z, Hirschfeld DR, Gleason S, Mirzadegan T, Dunten PW, Harris SF, Villasenor AG, Hang JQ, Heilek GM, Klumpp K. Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses. Bioorg Med Chem Lett. 2010 Jul 15;20(14):4215-8. Epub 2010 May 16. PMID:20538456 doi:10.1016/j.bmcl.2010.05.040

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