3lvp

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Image:3lvp.jpg

Template:STRUCTURE 3lvp

Crystal structure of bisphosphorylated IGF1-R Kinase domain (2P) in complex with a bis-azaindole inhibitor

Template:ABSTRACT PUBMED 20545947

About this Structure

3LVP is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Nemecek C, Metz WA, Wentzler S, Ding FX, Venot C, Souaille C, Dagallier A, Maignan S, Guilloteau JP, Bernard F, Henry A, Grapinet S, Lesuisse D. Design of potent IGF1-R inhibitors related to bis-azaindoles. Chem Biol Drug Des. 2010 Aug;76(2):100-6. Epub 2010 Jun 9. PMID:20545947 doi:10.1111/j.1747-0285.2010.00991.x

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