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3mks

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Image:3mks.jpg

Template:STRUCTURE 3mks

Crystal Structure of yeast Cdc4/Skp1 in complex with an allosteric inhibitor SCF-I2

Template:ABSTRACT PUBMED 20581844

About this Structure

3MKS is a 4 chains structure with sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Orlicky S, Tang X, Neduva V, Elowe N, Brown ED, Sicheri F, Tyers M. An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase. Nat Biotechnol. 2010 Jul;28(7):733-7. Epub 2010 Jun 27. PMID:20581844 doi:10.1038/nbt.1646

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