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Gelsolin

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Template:STRUCTURE 3ffn

3D Structure of Gelsolin


Contents

Actin Binding Protein

Gelsolin (GLS) is a protein regulator of actin assembly and disassembly. It contains 6 homologous domains S1 to S6. The image at the right is a of the Gelsolin

3D Structures of GLS

GLS

3ffn – hGLS – human
2fgh – hoGLS+ATP – horse
1d0n - hoGLS


GLS domains S1-S3

3ffk – hGLS domains S1-S3+actin
1rgi - hoGLS domains S1-S3+actin


GLS domains S4-S6

1h1v - hGLS domains S4-S6+actin
1nph - GLS domains S4-S6+Ca – mouse


GLS domain S1

2ff3 - hGLS domain S1+N-WASP+actin
2ff6 - hGLS domain S1+Ciboulot domain 2+actin
1mdu - hGLS domain S1+chActin – chicken
1d4x - hGLS domain S1+CeActin+Mg-ATP – Caenorhabditis elegans
1esv - hGLS domain S1+rActin+latrunculin – rabbit
1eqy - hGLS domain S1+rActin
1yvn - hGLS domain S1+yActin (mutant) – yeast
1yag - hGLS domain S1+yActin
1kcq – hGLS domainS1+Cd
1c0f - hGLS domain S1+DdActin+Ca-ATP - Dictyostelium discoideum
1c0g, 1dej - hGLS domain S1+DdActin (mutant)
3ci5, 3cip, 1nlv – DdGLS domain S1+actin
1nm1 - DdGLS domain S1+actin+Mg-ATP
3cjb - rGLS domain S1+rActin
3cjc - rGLS domain S1+rActin+DNAse I
1nmd - hGLS domain S1+actin+Ca+ATP


GLS C-terminal

2fh1, 2fh2, 2fh3, 2fh4 – hGLS C-terminal
1p8x - hGLS C-terminal+Ca
1p8z – hGLS fraction+rActin

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