3iit

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Image:3iit.jpg

Template:STRUCTURE 3iit

Factor XA in complex with a cis-1,2-diaminocyclohexane derivative

Template:ABSTRACT PUBMED 19900814

About this Structure

3IIT is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yoshikawa K, Kobayashi S, Nakamoto Y, Haginoya N, Komoriya S, Yoshino T, Nagata T, Mochizuki A, Watanabe K, Suzuki M, Kanno H, Ohta T. Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties. Bioorg Med Chem. 2009 Dec 15;17(24):8221-33. Epub 2009 Oct 17. PMID:19900814 doi:10.1016/j.bmc.2009.10.024

Page seeded by OCA on Wed Aug 4 09:06:20 2010

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