3d4q

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Image:3d4q.png

Template:STRUCTURE 3d4q

Pyrazole-based inhibitors of B-Raf kinase

Template:ABSTRACT PUBMED 18676143

About this Structure

3D4Q is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hansen JD, Grina J, Newhouse B, Welch M, Topalov G, Littman N, Callejo M, Gloor S, Martinson M, Laird E, Brandhuber BJ, Vigers G, Morales T, Woessner R, Randolph N, Lyssikatos J, Olivero A. Potent and selective pyrazole-based inhibitors of B-Raf kinase. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4692-5. Epub 2008 Jul 5. PMID:18676143 doi:10.1016/j.bmcl.2008.07.002

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