3kr8

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Template:STRUCTURE 3kr8

Human tankyrase 2 - catalytic PARP domain in complex with an inhibitor XAV939

Template:ABSTRACT PUBMED 20565110

About this Structure

3KR8 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Karlberg T, Markova N, Johansson I, Hammarstrom M, Schutz P, Weigelt J, Schuler H. Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor. J Med Chem. 2010 Jul 22;53(14):5352-5. PMID:20565110 doi:10.1021/jm100249w

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