3n2r

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Image:3n2r.png

Template:STRUCTURE 3n2r

Structure of neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R/3S,4S)-4-(3-Phenoxyphenoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine

Template:ABSTRACT PUBMED 20673724

About this Structure

3N2R is a 2 chains structure with sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Xue F, Huang J, Ji H, Fang J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB. Structure-based design, synthesis, and biological evaluation of lipophilic-tailed monocationic inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem. 2010 Sep 1;18(17):6526-37. Epub 2010 Jul 1. PMID:20673724 doi:10.1016/j.bmc.2010.06.074

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