3kwj

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Image:3kwj.jpg

Template:STRUCTURE 3kwj

Strucutre of human DPP-IV with (2S,3S,11bS)-3-(3-Fluoromethyl-phenyl)-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ylamine

Template:ABSTRACT PUBMED 20031408

About this Structure

3KWJ is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Boehringer M, Fischer H, Hennig M, Hunziker D, Huwyler J, Kuhn B, Loeffler BM, Luebbers T, Mattei P, Narquizian R, Sebokova E, Sprecher U, Wessel HP. Aryl- and heteroaryl-substituted aminobenzo[a]quinolizines as dipeptidyl peptidase IV inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1106-8. Epub 2009 Dec 6. PMID:20031408 doi:10.1016/j.bmcl.2009.12.025

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