3ocb

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Image:3ocb.jpg

Template:STRUCTURE 3ocb

Akt1 kinase domain with pyrrolopyrimidine inhibitor

Template:ABSTRACT PUBMED 20810279

About this Structure

3OCB is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Blake JF, Kallan NC, Xiao D, Xu R, Bencsik JR, Skelton NJ, Spencer KL, Mitchell IS, Woessner RD, Gloor SL, Risom T, Gross SD, Martinson M, Morales TH, Vigers GP, Brandhuber BJ. Discovery of pyrrolopyrimidine inhibitors of Akt. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5607-12. Epub 2010 Aug 13. PMID:20810279 doi:10.1016/j.bmcl.2010.08.053

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