3nrm

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Image:3nrm.png

Template:STRUCTURE 3nrm

Imidazo[1,2-a]pyrazine-based Aurora Kinase Inhibitors

Template:ABSTRACT PUBMED 20674350

About this Structure

3NRM is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Belanger DB, Curran PJ, Hruza A, Voigt J, Meng Z, Mandal AK, Siddiqui MA, Basso AD, Gray K. Discovery of imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5170-4. Epub 2010 Jul 8. PMID:20674350 doi:10.1016/j.bmcl.2010.07.008

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