2wi3
From Proteopedia
ORALLY ACTIVE 2-AMINO THIENOPYRIMIDINE INHIBITORS OF THE HSP90 CHAPERONE
Template:ABSTRACT PUBMED 19610616
About this Structure
2WI3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Brough PA, Barril X, Borgognoni J, Chene P, Davies NG, Davis B, Drysdale MJ, Dymock B, Eccles SA, Garcia-Echeverria C, Fromont C, Hayes A, Hubbard RE, Jordan AM, Jensen MR, Massey A, Merrett A, Padfield A, Parsons R, Radimerski T, Raynaud FI, Robertson A, Roughley SD, Schoepfer J, Simmonite H, Sharp SY, Surgenor A, Valenti M, Walls S, Webb P, Wood M, Workman P, Wright L. Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-d]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone. J Med Chem. 2009 Jul 17. PMID:19610616 doi:10.1021/jm900357y
Page seeded by OCA on Wed Sep 29 07:48:01 2010
Categories: Homo sapiens | Barril, X. | Borgognoni, J. | Brough, P A. | Chene, P. | Davies, N G.M. | Davis, B. | Drysdale, M J. | Dymock, B. | Eccles, S A. | Fromont, C. | Garcia-Echeverria, C. | Hayes, A. | Hubbard, R E. | Jordan, A M. | Massey, A. | Merret, A. | Padfield, A. | Parsons, R. | Radimerski, T. | Raynaud, F I. | Robertson, A. | Roughley, S D. | Rugaard-Jensen, M. | Schoepfer, J. | Simmonite, H. | Surgenor, A. | Valenti, M. | Walls, S. | Webb, P. | Wood, M. | Workman, P. | Wright, L M. | Chaperone | Heat shock | Nucleotide-binding | Stress response