2xru

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Image:2xru.jpg

Template:STRUCTURE 2xru

AURORA-A T288E COMPLEXED WITH PHA-828300

Template:ABSTRACT PUBMED 20817473

About this Structure

2XRU is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bindi S, Fancelli D, Alli C, Berta D, Bertrand JA, Cameron AD, Cappella P, Carpinelli P, Cervi G, Croci V, D'Anello M, Forte B, Giorgini ML, Marsiglio A, Moll J, Pesenti E, Pittala V, Pulici M, Riccardi-Sirtori F, Roletto F, Soncini C, Storici P, Varasi M, Volpi D, Zugnoni P, Vianello P. Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activity. Bioorg Med Chem. 2010 Oct 1;18(19):7113-20. Epub 2010 Jul 25. PMID:20817473 doi:10.1016/j.bmc.2010.07.048

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