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3o8i

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Image:3o8i.jpg

Template:STRUCTURE 3o8i

Structure of 14-3-3 isoform sigma in complex with a C-Raf1 peptide and a stabilizing small molecule fragment

Template:ABSTRACT PUBMED 20679480

About this Structure

3O8I is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Molzan M, Schumacher B, Ottmann C, Baljuls A, Polzien L, Weyand M, Thiel P, Rose R, Rose M, Kuhenne P, Kaiser M, Rapp UR, Kuhlmann J, Ottmann C. Impaired binding of 14-3-3 to C-RAF in Noonan Syndrome implies new approaches in diseases with increased Ras signaling. Mol Cell Biol. 2010 Aug 2. PMID:20679480 doi:10.1128/MCB.01636-09

Page seeded by OCA on Wed Sep 29 08:16:29 2010

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