3ncb

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Image:3ncb.png

Template:STRUCTURE 3ncb

A mutant human Prolactin receptor antagonist H180A in complex with the extracellular domain of the human prolactin receptor

Template:ABSTRACT PUBMED 20889499

About this Structure

3NCB is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kulkarni MV, Tettamanzi MC, Murphy JW, Keeler C, Myszka DG, Chayen NE, Lolis EJ, Hodsdon ME. Two independent histidines, one in human prolactin and one in its receptor, are critical for pH dependent receptor recognition and activation. J Biol Chem. 2010 Sep 30. PMID:20889499 doi:10.1074/jbc.M110.172072

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