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The high affinity of the noncovalent interaction between biotin and streptavidin forms the basis for many diagnostic assays that require the formation of an irreversible and specific linkage between biological macromolecules.

biotin and streptavidin

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==Your Heading Here (maybe something like 'Structure')==

Structure of HMG-CoA reductase (PDB entry 1dq8)

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