3oya

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Image:3oya.png

Template:STRUCTURE 3oya

Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and raltegravir at 2.65 resolution

Template:ABSTRACT PUBMED 20118915

About this Structure

3OYA is a 4 chains structure with sequences from Human spumaretrovirus. This structure supersedes the now removed PDB entry 3l2t. Full crystallographic information is available from OCA.

Reference

  • Hare S, Gupta SS, Valkov E, Engelman A, Cherepanov P. Retroviral intasome assembly and inhibition of DNA strand transfer. Nature. 2010 Mar 11;464(7286):232-6. Epub 2010 Jan 31. PMID:20118915 doi:10.1038/nature08784
  • Hare S, Vos AM, Clayton RF, Thuring JW, Cummings MD, Cherepanov P. Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance. Proc Natl Acad Sci U S A. 2010 Oct 28. PMID:21030679 doi:10.1073/pnas.1010246107

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