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3ipb

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Revision as of 08:05, 8 December 2010 by OCA (Talk | contribs)
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Image:3ipb.png

Template:STRUCTURE 3ipb

Human Transthyretin (TTR) complexed with a palindromic bivalent amyloid inhibitor (11 carbon linker).

Template:ABSTRACT PUBMED 21059958

About this Structure

3IPB is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Kolstoe SE, Mangione PP, Bellotti V, Taylor GW, Tennent GA, Deroo S, Morrison AJ, Cobb AJ, Coyne A, McCammon MG, Warner TD, Mitchell J, Gill R, Smith MD, Ley SV, Robinson CV, Wood SP, Pepys MB. Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proc Natl Acad Sci U S A. 2010 Nov 8. PMID:21059958 doi:10.1073/pnas.1008255107

Page seeded by OCA on Wed Dec 8 11:17:25 2010

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