3pa4

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Image:3pa4.jpg

Template:STRUCTURE 3pa4

X-ray crystal structure of compound 2a bound to human CHK1 kinase domain

Template:ABSTRACT PUBMED 21074424

About this Structure

3PA4 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhao L, Zhang Y, Dai C, Guzi T, Wiswell D, Seghezzi W, Parry D, Fischmann T, Siddiqui MA. Design, synthesis and SAR of thienopyridines as potent CHK1 inhibitors. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7216-21. Epub 2010 Oct 26. PMID:21074424 doi:10.1016/j.bmcl.2010.10.105

Page seeded by OCA on Wed Dec 8 11:54:10 2010

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